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Extra Super Avana

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Extra Super Avana is a combination medication containing Avanafil and Dapoxetine. It is designed to address both erectile dysfunction and premature ejaculation simultaneously. By improving blood flow and extending performance time, it helps men achieve better control and sexual health satisfaction.


Ingredients
Availability
In Stock
Delivery Time
Airmail (14-21 days) | EMS trackable (5-9 days)
Product is shipped in a fully discreet envelope with no content disclosure, including all required documentation inside

Product Sheet

Active Ingredient(s)
Avanafil, Dapoxetine
Manufacturer
Sunrise Remedies
Product Form
Tablet
Regulatory Classification
Rx
Primary Category
Men's Health, Sexual Health
Product Category
Urologicals, Drugs used in erectile dysfunction
Pharmacological Class
PDE5 inhibitor, Selective serotonin reuptake inhibitor (SSRI)
Manufacturer Description
A high-strength combination for managing both impotence and ejaculation control.
Mechanism of Action
Contains higher doses of both active ingredients to maximize blood flow to the genitals and provide maximum delay of climax through serotonin regulation.
Route of Administration
Oral
Onset Time
15-20 minutes
Duration
6 hours
Contraindications
Concomitant nitrates, Permanent cardiac pacing, Severe renal failure, History of syncope
Severe Adverse Events
Sudden loss of hearing, Painful erection lasting >4h, Severe hypotension
Common Side Effects
Headache, Flushing
Uncommon Side Effects
Nausea, Dizziness, Back pain
Drug Interactions
Nitrates, Alpha-blockers, CYP3A4 inhibitors
Pregnancy Safety Warnings
Not for use by women.
Age Restrictions
18-64 years.
Storage Guidelines
Keep in a cool, dry place.
Related Products
Spedra, Priligy

Extra Super Avana FAQ

Can I take Extra Super Avana with alcohol?

Moderate alcohol consumption is generally tolerated, but excessive drinking can increase dizziness, lower blood pressure, and reduce the effectiveness of avanafil. It is safest to limit alcohol intake around the time of sexual activity.

What does the tablet look like and are there imprint codes?

The tablet is a round, white pill embossed with the letters “EV” followed by the dosage strength “200/60”. Imprint codes help pharmacists verify authenticity.

Will Extra Super Avana show up on a drug test for work or sports?

Standard workplace drug screenings do not test for avanafil or dapoxetine. However, sports anti-doping agencies may consider avanafil a prohibited substance under certain circumstances; athletes should consult their governing body.

Is Extra Super Avana approved by the MHRA?

The individual ingredients, avanafil and dapoxetine, have separate MHRA approvals for ED and PE, respectively. The combination product Extra Super Avana does not have a distinct marketing authorization in the UK and is therefore used off-label.

How does the combination compare to taking two separate pills?

Combining the two agents into one tablet simplifies dosing and may improve adherence. Pharmacologically, the effect is equivalent to taking avanafil and dapoxetine separately, provided the same doses are used.

Can I travel internationally with this medication?

Yes, but keep the medication in its original packaging with a copy of the prescription. Some countries may require a doctor’s letter or may restrict import of PDE5 inhibitors and SSRIs; check local regulations before travel.

What should I do if I miss a dose and still plan to have sex later?

If a sexual encounter is not imminent, simply omit the dose. Do not double the dose later; take a new tablet only when you are ready for sexual activity, respecting the once-daily limit.

Are there any known drug interactions with common over-the-counter supplements? **

St. John’s wort induces CYP3A4 and can lower avanafil levels, reducing efficacy. Ginkgo biloba has mild antiplatelet activity and may increase bleeding risk when combined with nitrate therapy. Discuss all supplements with a pharmacist.

What is the typical cost difference between the combination and separate prescriptions?

Pricing varies by pharmacy and NHS prescribing policies. A combination tablet may reduce dispensing fees compared with two separate prescriptions, but exact cost depends on local formulary and patient eligibility for subsidies.

Can the tablet be split or crushed for easier swallowing?

The tablet should be swallowed whole. Splitting or crushing may alter the release profile and affect absorption, potentially reducing efficacy or increasing side-effect risk.

What is Extra Super Avana?

Extra Super Avana is a combination pill that contains two active ingredients: avanafil (200 mg) and dapoxetine (60 mg). The product is formulated as a single oral tablet and is intended for adult men who experience both erectile dysfunction (ED) and premature ejaculation (PE). In the United Kingdom the medication is classified as a Prescription-Only Medicine (POM) and must be prescribed by a qualified healthcare professional.

Because the brand name Extra Super Avana is not listed in publicly available regulatory databases, this article is based on the known properties of its component drugs-avanafil, a phosphodiesterase type 5 (PDE5) inhibitor, and dapoxetine, a short-acting selective serotonin reuptake inhibitor (SSRI).

How Extra Super Avana Works in the Body

Avanafil Component

Avanafil belongs to the PDE5 inhibitor class. It blocks the enzyme phosphodiesterase type 5, which normally degrades cyclic guanosine monophosphate (cG → cGMP) in the smooth muscle of the penile corpora cavernosa. By preserving cGMP levels, avanafil enhances nitric-oxide-mediated vasodilation, allowing increased blood flow into the penis and facilitating erection when sexual stimulation occurs.

  • Onset of action: 15-30 minutes after ingestion.
  • Peak effect: Approximately 1 hour.
  • Duration: Up to 12 hours, depending on individual metabolism.

Dapoxetine Component

Dapoxetine is a short-acting SSRI that increases synaptic serotonin by inhibiting its reuptake. Elevated serotonin activity in the central nervous system lengthens the ejaculatory latency time, helping men achieve better control over ejaculation.

  • Onset of action: 1-3 hours before sexual activity.
  • Half-life: About 1.5 hours, which limits systemic exposure and reduces the risk of long-term serotonergic side effects.

When taken together, the two agents target the two most common male sexual performance concerns: the ability to achieve a firm erection (via avanafil) and the ability to delay ejaculation (via dapoxetine).

Conditions Treated by Extra Super Avana

  • Erectile Dysfunction (ED): Avanafil is approved in the UK for the treatment of ED in adult males.
  • Premature Ejaculation (PE): Dapoxetine is approved for the treatment of PE in adult males.

Because the combination product itself does not have a separate marketing authorization, clinicians prescribe it off-label for patients who require simultaneous management of both conditions. The decision to use the combination should be made after a full clinical assessment and when monotherapy with either agent alone does not provide satisfactory outcomes.

Evidence-Based Off-Label Uses

Combined Therapy for Concurrent ED and PE

Small-scale clinical studies and observational reports have investigated the simultaneous use of a PDE5 inhibitor with dapoxetine in men who experience both ED and PE. These investigations suggest that combined therapy can improve overall sexual satisfaction compared with either drug alone. However, the evidence is limited to short-term trials and does not constitute formal regulatory approval.

  • Evidence level: Controlled trials (n < 200) with moderate methodological quality.
  • Regulatory status: Off-label; use requires careful patient selection and monitoring.

Off-label use requires medical supervision and individualized risk assessment.

Who Should (Not) Use Extra Super Avana?

Absolute Contraindications

  • Known hypersensitivity to avanafil, dapoxetine, or any tablet excipients.
  • Concurrent use of nitrates (e.g., nitroglycerin, isosorbide dinitrate) or nitric-oxide donors.
  • Use of any other serotonergic agents (e.g., other SSRIs, SNRIs, MAO inhibitors, tramadol, linezolid) due to risk of serotonin syndrome.
  • Uncontrolled severe hypertension (systolic > 180 mmHg or diastolic > 110 mmHg).
  • Grade III or higher heart failure (NYHA classification) or recent myocardial infarction (< 6 weeks).

Relative Contraindications

  • Moderate hepatic impairment (Child-Pugh B).
  • Moderate to severe renal impairment (eGFR < 30 mL/min/1.73 m²).
  • History of prolonged QT interval or other significant cardiac arrhythmias.
  • Concomitant use of potent CYP3A4 inhibitors (e.g., ketoconazole, itraconazole) that may increase avanafil plasma levels.

Special Populations

  • Pregnancy & lactation: Not applicable (therapy intended for adult males).
  • Elderly (≥ 65 years): Start at the lowest effective dose; monitor cardiovascular status closely.
  • Patients with hepatic or renal disease: Dose adjustments may be required; refer to prescribing information for avanafil and dapoxetine individually.

Safety Profile: Side Effects and Interactions

Common Side Effects

  • Headache - reported in up to 10 % of avanafil users.
  • Facial flushing - typical of PDE5 inhibition.
  • Nasal congestion - mild and transient.
  • Nausea - frequent with dapoxetine, especially when taken on an empty stomach.
  • Dizziness - can arise from either component; advise patients to rise slowly.

Serious Adverse Events

  • Priapism - prolonged erection > 4 hours; requires immediate medical attention.
  • Sudden loss of vision - rare but may indicate non-arteritic anterior ischemic optic neuropathy (NAION).
  • Serotonin syndrome - risk when combined with other serotonergic drugs; symptoms include agitation, hyperthermia, tachycardia, and neuromuscular abnormalities.
  • Severe hypotension - particularly when taken with nitrates or potent alpha-blockers.

Drug Interactions

  • Major: Nitrates, other PDE5 inhibitors, potent CYP3A4 inhibitors (e.g., ketoconazole, ritonavir), strong CYP2D6 inhibitors (affect dapoxetine metabolism).
  • Moderate: Alpha-blockers (e.g., tamsulosin), antihypertensives, other serotonergic agents (e.g., tramadol, triptans).
  • Mechanism: Avanafil is metabolised primarily by CYP3A4; dapoxetine by CYP2D6 and CYP3A4. Co-administration with inhibitors can raise systemic exposure and increase adverse-event risk.

Food and Lifestyle Interactions

  • Alcohol: Moderate consumption is generally tolerated, but excessive intake can worsen dizziness and hypotension.
  • High-fat meals: May delay avanafil absorption slightly; patients are advised to take the tablet with or without food according to personal tolerance.
  • Driving: Patients experiencing dizziness or visual changes should avoid operating machinery until they are certain the medication does not impair them.

How to Take Extra Super Avana

  • Standard dosing: One tablet (200 mg avanafil + 60 mg dapoxetine) taken orally about 15-30 minutes before anticipated sexual activity. The tablet should be swallowed whole with a glass of water.
  • Frequency: No more than once per day. Repeated dosing within 24 hours is not recommended.
  • Missed dose: If a sexual encounter is not anticipated, the dose can be omitted; do not take an extra tablet to "make up" a missed dose.
  • Renal impairment: For eGFR < 30 mL/min, consider reducing avanafil to 100 mg (if available) and evaluate dapoxetine suitability; consult a specialist.
  • Hepatic impairment: In moderate hepatic dysfunction, a lower dapoxetine dose (30 mg) may be advisable; avanafil dose reduction should be considered.
  • Overdose: Symptoms may include severe hypotension, prolonged erection, nausea, vomiting, and dizziness. Seek emergency medical care; there is no specific antidote, but supportive measures (IV fluids, blood pressure support) are used.
  • Discontinuation: The medication does not require tapering. However, patients should be advised to allow a wash-out period of at least 24 hours before initiating other serotonergic agents.

Monitoring and Follow-Up

  • Cardiovascular assessment: Blood pressure and heart rate should be measured before initiating therapy and periodically thereafter, especially in patients with known cardiovascular disease.
  • Liver function: Baseline hepatic enzymes are recommended for dapoxetine; repeat testing if clinically indicated.
  • Ejaculatory latency: Patients should be asked to report changes in ejaculation timing and any adverse sensations.
  • Adverse-event review: Prompt reporting of priapism, visual disturbances, or signs of serotonin syndrome is essential.

Storage and Handling

  • Store the tablet at room temperature (15 °C-30 °C), protected from moisture and direct sunlight.
  • Keep the container tightly closed and out of reach of children.
  • Do not use the medication after the expiry date printed on the package.
  • If a dose is missed and the tablet is past its expiry, dispose of it in accordance with local pharmacy guidelines; do not take an unexpired tablet from a previous pack.

Medication-Specific Glossary

Phosphodiesterase type 5 (PDE5) inhibitor
A class of drugs that block the PDE5 enzyme, preserving cGMP and enhancing penile blood flow during sexual stimulation.
Selective serotonin reuptake inhibitor (SSRI)
A type of antidepressant that increases serotonin levels in the brain by inhibiting its reabsorption into nerve cells; dapoxetine is a short-acting SSRI used for premature ejaculation.
Priapism
A prolonged, often painful erection lasting more than four hours, unrelated to sexual arousal, requiring urgent medical treatment.
Serotonin syndrome
A potentially life-threatening condition caused by excess serotonergic activity, characterized by agitation, hyperthermia, increased reflexes, and autonomic instability.
Therapeutic window
The dosage range in which a medication provides optimal efficacy with minimal adverse effects.

Medical Disclaimer

This article provides educational information about Extra Super Avana and is not a substitute for professional medical advice. Treatment decisions, including use for unapproved indications, must be made under the guidance of a qualified healthcare provider. The content is intended for informational purposes and does not constitute medical recommendations. Always consult a physician before starting, stopping, or changing any medication regimen.

Information for Extra Super Avana is sourced from established medical standards and updated frequently. It is provided for general guidance and should be confirmed with a healthcare professional before use.
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