Buy Viagra with Dapoxetine
Viagra with Dapoxetine

1.48
Viagra with Dapoxetine is a combined treatment designed for adult men experiencing erectile dysfunction and premature ejaculation. Sildenafil works by relaxing pelvic blood vessels, while Dapoxetine targets the causes of early climax. Together, they help restore confidence and enhance the duration of physical activity.


Availability
In Stock
Delivery Time
Airmail (14-21 days) | EMS trackable (5-9 days)
Product is shipped in a fully discreet envelope with no content disclosure, including all required documentation inside

Product Sheet

Active Ingredient(s)
Sildenafil, Dapoxetine
Product Form
Tablet
Regulatory Classification
Rx
Primary Category
Men's Health, Sexual Health
Product Category
Urologicals, Drugs used in erectile dysfunction
Pharmacological Class
PDE5 inhibitor, SSRI
Manufacturer Description
Dual-action medicine to help with staying power and achieving an erection.
Mechanism of Action
Combined action where sildenafil aids erection via enzyme inhibition and dapoxetine delays climax by prolonging serotonin action in the nervous system.
Route of Administration
Oral
Onset Time
30-60 minutes
Duration
4-6 hours
Contraindications
Nitrates, Heart failure, Severe liver disease, Use of MAOIs
Severe Adverse Events
Prolonged erection, Seizures, Severe mood changes
Common Side Effects
Nausea, Headache
Uncommon Side Effects
Dizziness, Flushing, Insomnia
Drug Interactions
Nitrates, Antidepressants, Erythromycin
Pregnancy Safety Warnings
Not for use by women.
Age Restrictions
18-64 years.
Storage Guidelines
Store in a cool, dry place.
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Viagra with Dapoxetine FAQ

Can I travel internationally with Viagra with Dapoxetine?

Yes, the medication can be carried in hand luggage for personal use, but you should keep it in its original packaging with a prescription label. Some countries restrict import of combination products not approved locally, so verify entry rules before departure.

Will this pill show up on a workplace drug test?

Standard occupational drug screens do not test for sildenafil or dapoxetine. However, if a test specifically screens for prescription medications, the presence of either compound may be reported.

What does the pill look like and how can I identify it?

The combination tablet is typically round, film-coated, and bears a distinctive imprint code (e.g., “100/60”) on one side. The colour and size may vary by manufacturer; always compare with the pharmacy-provided description.

How does taking the combined pill differ from taking separate sildenafil and dapoxetine tablets?

The combined pill delivers a fixed dose of 100 mg sildenafil and 60 mg dapoxetine, simplifying timing and reducing the number of pills taken before intercourse. Pharmacologically, the effect is equivalent to taking the two agents separately, provided the same doses are used.

How long do the effects of the combination last?

Sildenafil’s erection-facilitating effect lasts up to 4-6 hours, while dapoxetine’s ejaculatory-control effect peaks 1-3 hours after ingestion and dissipates within 6 hours due to its short half-life.

Is it safe to drink alcohol while using this medication?

Moderate alcohol consumption (up to one standard drink) is generally tolerated, but excessive intake may enhance vasodilatory effects, leading to dizziness or reduced erectile response. Use caution and avoid binge drinking.

Can men with high blood pressure use Viagra with Dapoxetine?

If blood pressure is well controlled (≤ 150/90 mmHg) and the patient is not on nitrate therapy, the combination can be used cautiously. Uncontrolled hypertension is a contraindication and requires optimisation before prescribing.

Does the medication affect male fertility?

Current evidence shows no adverse impact on sperm count or motility from short-term use of sildenafil or dapoxetine. Long-term data are limited, so discuss any concerns with a specialist.

Why is this product not approved by the MHRA?

The MHRA has not evaluated the fixed-dose combination of sildenafil and dapoxetine for safety and efficacy within the UK regulatory framework. Individual components are approved separately (sildenafil) or not at all (dapoxetine) for the indicated uses.

Are there cost differences between the combination pill and separate prescriptions?

Pricing varies by pharmacy and NHS prescribing policies. In some cases, a single combination tablet may be more convenient but not necessarily cheaper than two separate prescriptions. Patients should discuss cost considerations with their prescriber or pharmacist.

Viagra with Dapoxetine: Pill 100/60 mg - Overview for Adults in the UK

Introduction

Viagra with Dapoxetine combines two active ingredients - sildenafil and dapoxetine - into a single oral pill (100 mg/60 mg). Sildenafil is a phosphodiesterase-5 (PDE5) inhibitor approved for the treatment of erectile dysfunction (ED). Dapoxetine is a short-acting selective serotonin reuptake inhibitor (SSRI) that is approved in several European countries for premature ejaculation (PE).

In the United Kingdom the Medicines and Healthcare products Regulatory Agency (MHRA) has not approved this specific combination product. Sildenafil-only tablets (Viagra) are available on prescription, and dapoxetine is not licensed for use in the UK. Consequently, any use of the combined 100 mg/60 mg pill would be considered off-label and should be managed by a specialist prescriber after a thorough risk-benefit assessment.

The pill is supplied as a standard oral tablet; no special administration devices are required.

How Viagra with Dapoxetine Works in the Body

Pharmacology of Sildenafil

  • Target: Inhibits the enzyme PDE5 in the corpus cavernosum.
  • Result: Prevents breakdown of cyclic guanosine monophosphate (cGMP), allowing smooth-muscle relaxation and increased blood flow to the penis during sexual stimulation.
  • Onset: Usually 30-60 minutes after ingestion; peak effect at about 1 hour.
  • Duration: Effects may last up to 4-6 hours, depending on dose and individual metabolism.

Pharmacology of Dapoxetine

  • Target: Blocks the reuptake of serotonin (5-HT) at neuronal synapses, leading to a modest increase in serotonergic signalling.
  • Result: Enhances ejaculatory control by prolonging the time to reach the ejaculatory threshold.
  • Onset: Typically 1-3 hours after ingestion.
  • Duration: The drug is eliminated rapidly (half-life ≈ 1.5 hours), which limits systemic exposure and reduces the risk of long-term serotonergic side effects.

When taken together, sildenafil facilitates a sufficient erection, while dapoxetine extends the latency to ejaculation, addressing both components of sexual performance in a single dose.

Conditions Treated by Viagra with Dapoxetine

  • Erectile Dysfunction (ED): Impaired ability to achieve or maintain an erection sufficient for satisfactory sexual activity.
  • Premature Ejaculation (PE): Ejaculation that occurs sooner than desired, often within one minute of penetration, causing personal distress or relationship difficulty.

Both indications are recognised by the European Medicines Agency (EMA) for the individual agents, but the combined formulation has not received a separate marketing authorisation in the UK.

Off-Label and Investigational Applications

The combination has been explored in clinical studies conducted primarily in Spain and Italy, where it is marketed under specific brand names. Evidence suggests improved patient-reported satisfaction when both ED and PE are present, compared with using either agent alone.

  • Evidence Level: Small-scale randomised controlled trials (n ≈ 100-200) have demonstrated statistically significant increases in intravaginal ejaculatory latency time (IELT) and erection quality scores.
  • Regulatory Status: Not approved by the MHRA; off-label use requires specialist supervision and written informed consent.

Who Should (Not) Use Viagra with Dapoxetine?

Absolute Contra-indications

  • Known hypersensitivity to sildenafil, dapoxetine, or any excipients in the tablet.
  • Concomitant use of nitrates (e.g., nitroglycerin) or nitric-oxide donors.
  • Severe uncontrolled hypertension (systolic > 180 mmHg or diastolic > 110 mmHg).
  • Recent (within 6 weeks) myocardial infarction, stroke, or life-threatening arrhythmia.
  • History of non-arteritic anterior ischemic optic neuropathy (NAION).
  • Current use of monoamine-oxidase inhibitors (MAOIs) or other serotonergic agents (e.g., other SSRIs, tramadol, linezolid).

Relative Contra-indications

  • Age > 65 years - start with the lowest effective dose and monitor cardiovascular status.
  • Moderate hepatic impairment (Child-Pugh B) - dose reduction may be needed.
  • Moderate renal impairment (creatinine clearance 30-50 mL/min) - consider dose adjustment.
  • History of depression or suicidal ideation - dapoxetine may exacerbate mood symptoms.
  • Concurrent use of potent CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin).

Special Populations

  • Pregnancy & Lactation: Not applicable to the male patient, but partner exposure is negligible; however, advise against handling broken tablets without gloves.
  • Pediatric Use: Not indicated.
  • Geriatric Considerations: Assess cardiovascular risk and renal/hepatic function before prescribing.

Safety Profile: Side Effects and Interactions

Common Side Effects

  • Headache - reported in up to 15 % of users.
  • Facial flushing - transient warmth, usually resolves without intervention.
  • Indigestion or dyspepsia - may be reduced by taking the tablet with food.
  • Nasal congestion - mild, self-limiting.
  • Nausea - more frequently linked to dapoxetine.

Serious Adverse Events

  • Priapism (erection lasting > 4 hours) - requires immediate medical attention to prevent permanent damage.
  • Sudden loss of vision or hearing - rare but warrants urgent evaluation.
  • Serotonin syndrome - risk when combined with other serotonergic drugs; signs include agitation, hyperreflexia, tremor, and fever.
  • Cardiovascular events - chest pain or palpitations, especially in patients with underlying heart disease.

Drug Interactions

  • Major: Nitrates (absolute contraindication).
  • Moderate: Alpha-blockers (e.g., tamsulosin) - may cause additive blood-pressure lowering; monitor.
  • CYP3A4 inhibitors (ketoconazole, ritonavir) - increase sildenafil plasma concentrations; consider dose reduction.
  • CYP2D6 inhibitors (paroxetine, quinidine) - may elevate dapoxetine levels; monitor for increased nausea or dizziness.
  • Other serotonergic agents (tramadol, tramadol, St. John’s wort) - raise risk of serotonin syndrome; avoid co-administration.

Food and Lifestyle Interactions

  • High-fat meals can delay sildenafil absorption, shifting onset by up to 30 minutes.
  • Alcohol in moderate amounts may potentiate vasodilatory effects, leading to dizziness or hypotension.
  • Driving or operating machinery: Patients should assess their own tolerance; dizziness is possible, especially after the first dose.

How to Take Viagra with Dapoxetine

  • Standard regimen: One tablet (100 mg sildenafil + 60 mg dapoxetine) taken orally about 1 hour before anticipated sexual activity.
  • Frequency: Do not exceed one tablet in a 24-hour period.
  • With or without food: Acceptable either way; a heavy, fatty meal may delay onset of the sildenafil component.
  • Missed dose: If the planned activity does not occur, do not take an additional tablet later in the day; simply wait until the next 24-hour cycle.
  • Renal adjustment: For creatinine clearance < 30 mL/min, a lower dose of sildenafil (e.g., 50 mg) is often recommended; dapoxetine is not recommended in severe renal impairment.
  • Hepatic adjustment: In moderate hepatic dysfunction, consider reducing the sildenafil dose to 50 mg; dapoxetine is contraindicated in severe hepatic disease.
  • Overdose signs: Severe headache, hypotension, priapism, fainting, or prolonged nausea. Seek emergency medical care; there is no specific antidote, but supportive measures (e.g., intravenous fluids, vasopressors) are used.
  • Discontinuation: No tapering required; stop use if intolerable side effects occur.

Monitoring and Follow-Up

  • Baseline assessment: Blood pressure, cardiovascular history, and review of concomitant medications.
  • Follow-up visit: 2-4 weeks after initiation to evaluate efficacy (erection quality, ejaculatory latency) and tolerability.
  • Laboratory tests: No routine labs are required for healthy adults, but liver function tests are advisable in patients with known hepatic disease.
  • When to seek urgent care: Persistent erection > 4 hours, sudden vision or hearing loss, severe chest pain, or signs of serotonin syndrome.

Storage and Handling

  • Keep the tablets in the original blister pack until use.
  • Store at ≤ 30 °C, away from moisture and direct sunlight.
  • Do not freeze.
  • Keep out of reach of children and pets.
  • Dispose of unused tablets according to local pharmacy-take-back schemes or follow the “take-back” instructions on the packaging.

Medication-Specific Glossary

PDE5 (Phosphodiesterase-5)
An enzyme that degrades cGMP in penile tissue; inhibition by sildenafil leads to prolonged smooth-muscle relaxation and erection.
SSRI (Selective Serotonin Reuptake Inhibitor)
A class of antidepressants that increase serotonin levels by blocking its reabsorption; dapoxetine is a short-acting SSRI used for premature ejaculation.
Priapism
A prolonged, often painful erection lasting more than four hours, which can cause permanent tissue damage if not treated promptly.
Serotonin Syndrome
A potentially life-threatening condition caused by excess serotonergic activity, characterised by agitation, hyperreflexia, fever, and autonomic instability.

Medical Disclaimer

This article provides educational information about Viagra with Dapoxetine and is not a substitute for professional medical advice. Treatment decisions, including use for unapproved indications, must be made under the guidance of a qualified healthcare provider. The content is intended for informational purposes and does not constitute medical recommendations. Always consult a physician before starting, stopping, or changing any medication regimen.

Information for Viagra with Dapoxetine is sourced from established medical standards and updated frequently. It is provided for general guidance and should be confirmed with a healthcare professional before use.
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